Quick Answer: What Is The Rarest Disease In History?

How rare is a rare disease?

In the United States, a rare disease is defined as a condition that affects fewer than 200,000 people in the US.

This definition was created by Congress in the Orphan Drug Act of 1983.

Rare diseases became known as orphan diseases because drug companies were not interested in adopting them to develop treatments..

What mental illness does the Joker have?

What do you do for the Joker? He has bipolar disorder type 1, most recent episode manic, severe, with psychotic features, and he also has Pseudobulbar affect. That can be treated by medication.

What is the rarest mental disorder?

Apotemnophilia. Also known as body integrity identity disorder, apotemnophilia is characterized by the “overwhelming desire to amputate healthy parts of [the] body,” according to Medscape. Though not much is known about it, this disorder is believed to be neurological.

What are the six killer diseases of a child?

These six are the target diseases of WHO’s Expanded Programme on Immuni- zation (EPI), and of UNICEF’s Univer- sal Childhood Immunization (UCI); measles, poliomyelitis, diphtheria, pertussis (whooping cough), tetanus and tuberculosis.

What causes Hallermann Streiff syndrome?

The genetic cause of Hallermann–Streiff syndrome has not been conclusively determined. It is most likely due to a de novo mutation, and it may be associated with the GJA1 gene.

What are the top 10 rarest diseases?

Here is a list of seven rare diseases around the world which you should be aware of:Hutchinson-Gilford Progeria. … Fields’ Disease. … Fibrodysplasia Ossificans Progressiva. … Von Hippel-Lindau. … Microcephaly. … Paraneoplastic Pemphigus. … Morgellons.

What is the weirdest disease in the world?

Water allergy. … Foreign accent syndrome. … Laughing Death. … Fibrodysplasia ossificans progressiva (FOP) … Alice in Wonderland syndrome. … Porphyria. … Pica. … Moebius syndrome. Moebius is extremely rare, genetic and characterized by complete facial paralysis.More items…•

What is the most common disease?

So, without further ado, here are the five most common infectious diseases.Hepatitis B. According to current statistics, hepatitis B is the most common infectious disease in the world, affecting some 2 billion people — that’s more than one-quarter of the world’s population. … Malaria. … Hepatitis C. … Dengue. … Tuberculosis.

What is the hardest mental illness to live with?

Personality disorders are among the most difficult forms of mental illness to treat. Often, people with these disorders don’t seek help because they are able to function in their day-to-day lives.

What is the number 1 mental illness?

Depression. Impacting an estimated 300 million people, depression is the most-common mental disorder and generally affects women more often than men.

What are examples of rare diseases?

Examples of rare diseases caused by mutations in single genes include cystic fibrosis, which affects the respiratory and digestive systems (See: Learning About Cystic Fibrosis); Huntington’s disease, which affects the brain and nervous system (See: Learning About Huntington’s Disease); and muscular dystrophies, which …

How many rare diseases are there in the world?

There are between 5 000 and 8 000 rare diseases, most of them with a genetic basis. 1 A very rough estimate would be that one out of 15 persons worldwide could be affected by a rare (“orphan”) disease – 400 million people worldwide, of whom 30 million are in Europe and 25 million in the United States.